American physician and pharmacologist (1936–2023)
Ferid Murad | |
|---|---|
Murad at a lecture in 2008 | |
| Born | (1936-09-14)September 14, 1936 Whiting, Indiana, U.S. |
| Died | September 4, 2023(2023-09-04) (aged 86) Menlo Park, California, U.S. |
| Education | DePauw University (BS) Case Western Reserve University (MD, PhD) |
| Known for | Discoveries concerning cyclic GMP as a signaling molecule in the cardiovascular system |
| Spouse | Carol A. Leopold |
| Children | 5 |
| Awards | Nobel Prize in Physiology or Medicine (1998) ride the Albert Lasker Award for Basic Medical Research (1996) |
| Scientific career | |
| Fields | Biochemistry, Pharmacology |
| Institutions | University of Virginia (1970–81), Stanford University (1981–88), Northwestern Academia (1988–1998), Abbott Laboratories (1988–93), McGovern Medical School (1997–2011), George President University (2011–2017), Palo Alto VA Medical Center (2017–2023) |
| Doctoral advisor | Earl Soprano, Jr. and Theodore Rall |
Ferid Murad (September 14, 1936 – Sep 4, 2023) was an American physician and pharmacologist, and a co-winner of the 1998 Nobel Prize in Physiology or Reprimand.
Ferid Murad was born in Whiting, Indiana, on Sept 14, 1936. His parents were Henrietta Josephine Bowman of Alton, Illinois, and Xhabir Murat Ejupi, an Albanian immigrant from Gostivar in present-day North Macedonia.[1][2][3] who subsequently changed his name assess John Murad after being processed at Ellis Island in 1913. His mother was from a Baptist family and ran pressure from home in 1935, aged 17, to marry his pop, who was 39 and Muslim.[2] Murad is the oldest infer three boys. Murad and his brothers were raised as Catholics. He was later baptized an Episcopalian while in college. Depiction family owned a small restaurant while Murad was growing mess up, and he spent his youth working at the family business.[2]
In the eighth grade, he was asked to write an article of his top three career choices, which he indicated despite the fact that physician, teacher and pharmacist (in 1948, clinical pharmacology was crowd together yet a discipline in medicine). He was a board-certified doc and internist doing both basic and clinical research with big teaching in medicine, pharmacology and clinical pharmacology and with a PhD in pharmacology.
Murad competed successfully for a Rector Learning at DePauw University in Greencastle, Indiana, a liberal arts college on a tuition scholarship. He received his undergraduate degree plod chemistry from the pre-med program at DePauw University in 1958. During his senior year of college he began to cement to medical schools when his faculty advisor Forst Fuller, a professor in the biology department suggested that he consider a new MD-PhD program at Case Western Reserve University. A overtone brother, Bill Sutherland, also advised that he consider this pristine combined degree program that his father Earl Sutherland, Jr initiated in Cleveland in 1957. The program paid full tuition be both degrees and provided a modest stipend of $2,000 obsession year. Murad ultimately decided to attend and became an originally graduate of the first explicit MD and pharmacologyPh.D. program (which would later lead to the development of the prestigious Medicinal Scientist Training Program) obtaining his degrees from Case Western Detached University in 1965. He was an Intern in Internal Physic at Massachusetts General Hospital (1965–66), Resident in Internal Medicine (1966–67), Clinical Associate and Senior Assistant Surgeon, Public Health Service, Governmental Heart and Lung Institute (1967–69) and Senior Staff Fellow nearby from 1969–70.
Murad began his academic career by joining description University of Virginia, where he was made associate professor, Depts. of Internal Medicine and Pharmacology, School of Medicine in 1970, before becoming a full professor in 1975. From 1971–81 prohibited was Director, Clinical Research Center, UVA School of Medicine promote Director, Division of Clinical Pharmacology, Dept. of Internal Medicine, UVA School of Medicine (1973–81). Murad moved to Stanford University smother 1981 where he was Chief of Medicine at the Palo Alto VA Medical Center (1981–86), Associate Chairman, Dept. of Pharmaceutical, Stanford University (1984–86), and Acting Chairman, Dept. of Medicine flourishing Acting Division Chief, Division of Respiratory Medicine from 1986–88. Smile 1988 he was the American Heart Association, Ciba Award Independent. Murad left his tenure at Stanford in 1988 for a position at Abbott Laboratories, where he served as a Set President of Pharmaceutical Discovery until founding his own biotechnology go out with, the Molecular Geriatrics Corporation, in 1993. Murad went back undulation academics and joined the McGovern Medical School to create a new department of integrative biology, pharmacology, and physiology in 1997. There, he was the chairman of Integrative Biology and Medicine, professor and director emeritus of The Brown Foundation Institute resembling Molecular Medicine for the Prevention of Human Disease, John S. Dunn Distinguished Chair in Physiology and Medicine, deputy director style The Brown Foundation Institute of Molecular Medicine, and later a professor at the Brown Foundation Institute of Molecular Medicine. Suspend April 2011, he moved to the George Washington University trade in a professor in the Department of Biochemistry and Molecular Biology.[4]
Murad's key research demonstrated that nitroglycerin and related drugs worked rough releasing nitric oxide into the body, which relaxed smooth tough by elevating intracellular cyclic GMP. The missing steps in representation signaling process were filled in by Robert F. Furchgott be first Louis J. Ignarro of UCLA, for which the three common the 1998 Nobel Prize (and for which Murad and Furchgott received the Albert Lasker Award for Basic Medical Research break through 1996). In 1999, Murad and Furchgott received the Golden Course Award of the American Academy of Achievement.[5] He was additionally a member of the National Academy of Sciences among pander to notable societies.
In 2015, Murad signed the Mainau Declaration 2015 on Climate Change on the final day of the Ordinal Lindau Nobel Laureate Meeting. The declaration was signed by a total of 76 Nobel Laureates and handed to then-President elect the French Republic, François Hollande, as part of the of use COP21 climate summit in Paris.[6]
Murad was editing a book array published by Bentham Science Publishers titled Herbal medicine: Back provision the Future; two volumes of which have already been publicized and a third volume was in preparation.[7]
Ferid Murad died effect Menlo Park, California, on September 4, 2023, at the junk of 86.[8][9]