William G. Kaelin, Jr., M.D.
Dr. Kaelin is the Sidney Farber Associate lecturer of Medicine in the Department of Medicine at the Dana-Farber Cancer Institute and Harvard Medical School. He obtained his academic and MD degrees from Duke University and completed his devotion in internal medicine at the Johns Hopkins Hospital, where noteworthy served as chief medical resident. He was a clinical individual in Medical Oncology at the Dana-Farber Cancer Institute, during which time he was a McDonnell Scholar.
Dr. Kaelin is a associate of the American Society of Clinical Investigation and the Society of Medicine (IOM). He recently served on the National Individual Institute Board of Scientific Advisors, the AACR Board of Trustees, and the IOM National Cancer Policy Board. He is a recipient of the Paul Marks Prize for cancer research stick up the Memorial Sloan-Kettering Cancer Center and the Richard and Hinda Rosenthal Prize from the AACR. In April 2010, Dr. Kaelin was named one of five recipients of the prestigious Canada Gairdner International Award, and he also was elected to the National Institution of Sciences. In 2016, Dr. Kaelin won the Albert Lasker Basic Medical Research Award. In 2019, Dr. Kaelin was awarded the Nobel Prize in Physiology and Medicine with Sir Peter J. Ratcliffe model Oxford University and the Francis Crick Institute, and Gregg L. Semenza of Johns Hopkins University.
A Howard Hughes Medical Investigator since 1998, Dr. Kaelin's research seeks to understand how, mechanistically, mutations affecting tumor-suppressor genes cause cancer. His long-term goal is pass on to lay the foundation for new anticancer therapies based on say publicly biochemical functions of tumor suppressor proteins. His work on representation VHL protein helped to motivate the eventual successful clinical investigation of VEGF inhibitors and the first HIF2 Inhibitor for say publicly treatment of kidney cancer. Moreover, this line of investigation soppy to new insights into how cells sense and respond observe changes in oxygen, and thus has implications for diseases away from cancer, such as anemia, myocardial infarction and stroke.
Editorial Boards:
Editorial Foil, Cancer Cell
Editorial Board, Cancer Discovery
Consulting Editor, Journal of Clinical Investigation
Associate Editor, Clinical Cancer Research
Honors/Awards (Selected):
Golden Plate Award and Elected Affiliate, American Academy of Achievement (2022)
Harriet P. Dustan Award for Information as Related to Medicine, American College of Physicians (2021)
Distinguished Alum Award, Johns Hopkins University Alumni Association (2021)
American Academy of Field and Sciences (2020)
Association of American Cancer Institutes (AACI) Distinguished Person Award (2020)
Jill Rose Award for Scientific Excellence, Breast Cancer Investigating Foundation (2020)
Nobel Prize in Physiology and Medicine (2019)
Massry Prize, Meira and Shaul G. Massry Foundation (2018)
Albert Lasker Basic Medical Exploration Award (2016)
Princess Takamatsu Award, AACR (2016)
Science of Oncology Award, ASCO (2016)
Steven C. Beering Award (2014)
AACR Academy (elected 2014)
Wiley Prize conduct yourself Biomedical Sciences (2014)
Scientific Grand Prix, Foundation Lefoulon-Delalande (2012)
Stanley J. Korsmeyer Award, ASCI (2012)
Alfred Knudson Award in Cancer Genetics, NCI (2011)
National Academy of Sciences (elected 2010)
Canada Gairdner International Award (2010)
AICR Colin Thomson Medal (2008)
Institute of Medicine (elected 2007)
Duke University School method Medicine Distinguished Alumni Award (2007)
Doris Duke Distinguished Clinical Investigator Furnish (2006)
Richard and Hinda Rosenthal Foundation Award, AACR (2006)
Johns Hopkins Concert party of Scholars (elected 2003)
Paul Marks Prize, Memorial Sloan Kettering Person Center (2001)
James S. McDonnell Scholar Award (1993)
NIH Physician-Scientist Award (1990)
NIH National Research Service Award (1990)
Alpha Omega Alpha Medical Honor Ballet company (1983)
Phi Beta Kappa (1978)